Colorectal Cancer Association of Canada - CCAC
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Anal Cancer > Risk Factors  

There are several factors which may increase the risk of developing the most common type anal cancer – squamous cell anal cancer. These include the following:

  • Infection with human papillomavirus (HPV)
  • Having multiple sexual partners
  • Having receptive anal intercourse (anal sex)
  • Smoking cigarettes
  • Frequent anal redness, swelling, and soreness
  • Having anal fistulas (abnormal openings)
  • Lowered Immunity (i.e. people living with HIV, organ transplants, immunosuppressive drugs)

Some people may not have may not have any risk factors at all and will still develop anal cancer.

Source: National Cancer Institute (http://www.cancer.gov/cancertopics/pdq/treatment/anal/Patient/page1) Cancer Net http://www.cancer.net/cancer-types/anal-cancer/risk-factors-and-prevention